Exercises and postures
Activities such as walking, swimming, stretching, and aerobic exercises are good for protecting the spine and relieving back pain. Exercises can strengthen the body and prevent back pain. Exercises such as curl-ups, press-ups, sit-ups, and hamstring stretch are especially helpful for back problems. Stomach-strengthening exercises such as using abdominal rollers can strengthen abdominal [...] http://digg.com/u1J0IF
Back pain affects millions of Americans and can be caused by many reasons. Back pain includes acute and chronic types. Acute back pain occurs quickly and may be caused by movements or injuries. Chronic back pain often comes and goes. Acute back pain may sometimes become chronic.
Strain, overuse, or improper movement may sprain the ligaments, [...] http://digg.com/u1IsFI
Diets and foods
Proper diets, nutrition, and stress reduction are essential for the prevention and healing of arthritis. Vegetarian diets may help reduce inflammation, while animal fats may increase inflammatory responses. Fatty meats and dairy products are suggested to be reduced in diets for arthritis patients. Tobacco, alcohol, and caffeine need to be completely avoided, especially [...] http://digg.com/u1Io0i
* ABP1
Full Name:
amiloride binding protein 1 (amine oxidase (copper-containing)) [Homo sapiens]
Other Symbols:
ABP, AOC1, DAO, DAO1, KAO
Other Names:
amiloride binding protein 1; amiloride-binding protein; amiloride-binding protein-1; amiloride-sensitive amine oxidase; diamine oxidase; histaminase; kidney amine oxidase
Chromosome Location:
7q34-q36
OMIMID:
104610
GeneID:
26
Disease association:
The protein may be associated with the level of histamine and food allergy.
Reference:
- Analysis of [...] http://digg.com/u1Ikcc
Arthritis is a disorder of joints and connective tissue with inflammatory symptoms of pain, stiffness, and swelling. Serious arthritis may result in crippling and disability. Older people are affected by arthritis more often than younger people, although the disease may occur at any age. There are more than 100 types of arthritis disorders.
Osteoarthritis
The most common [...] http://digg.com/u1Ide9
Healthy eating habits
What and how a person eats are often more important than how much a person eats. Having regular meals is important for maintaining a healthy weight. Skipping meals, overeating, or taking snacks are not good habits for weight management. Skipping meals often have opposite effects, as the sense of deprivation of food may [...] http://digg.com/u1IXfI
Here is the formula to find out the basal metabolic rate (BMR) and the necessary calories to maintain basic physiological functions such as heart beat and body temperature:
For women: BMR = Weight (in kilograms) X 0.9 X 24
For men: BMR = Weight (in kilograms) X 24
An approximate calculation of the calories you need:
For sedentary people: [...] http://digg.com/u1ITKM
Obesity, other diseases, and aging
Obesity is associated with other diseases including high cholesterol, high blood pressure, type 2 diabetes, heart disease, ischemic stroke, gallstones, low-back pain, arthritis, and cancers. Sometimes losing just five to ten percent of the body weight can reduce the risks for developing other diseases such as heart disease and hypertension.
Obesity is [...] http://digg.com/u1IPEd
Nutritional supplements
Nutritional supplements can be helpful for relieving Alzheimer’s disease. Because free radical damages play an important role in Alzheimer’s disease, antioxidants such as vitamins A, C, and E, as well as selenium may neutralize free radical damages and reduce the damages. Foods that are rich in these antioxidants include raisins, raspberries, strawberries, blueberries, blackberries, [...] http://digg.com/u1IFs5
About 5 million Americans have Alzheimer’s disease. More than 50 percent of dementia cases are caused by Alzheimer’s disease. About 20 percent of 75-84 year old people have Alzheimer’s disease, and about 50 percent of those older than 85 have the disease.
Alzheimer’s disease is a progressive and degenerative disorder of the brain. The disease impairs [...] http://digg.com/u1ID9J
Changing lifestyles can help prevent and heal allergies. Avoid allergens is one of the most important ways. Avoid foods and foods containing the ingredients that may cause allergies. Exercise inside home to avoid high pollen during allergy season. Wash bedding in hot water weekly can help avoid dust mites. Cover the mattress and box spring [...] http://digg.com/u1I9OD
The abnormal immune responses are shown as symptoms on the parts of the body that usually have contacted the allergens. More than ten percent of Americans are affected by allergic rhinitis. For example, airborne pollen from trees, grasses, or weeds may cause seasonal allergic rhinitis such as hay fever shown as sneezing, stuffy or runny [...] http://digg.com/u1I9H0
About twenty percent of Americans are allergic to something. Allergies may contribute to other diseases including bronchitis, gastrointestinal disorders, kidney problems, obesity, diabetes, palpitation, rheumatoid arthritis, headaches and migraines, depression, and eczema.
The most common factors of allergies are particles floating in the air, such as pollen. The most common allergy is hay fever. Allergies are [...] http://digg.com/u1I7Hq
The privacy of our visitors to PharmTao.com is important to us.
At PharmTao.com, we recognize that privacy of your personal information is important. Here is information on what types of personal information we receive and collect when you use and visit PharmTao.com, and how we safeguard your information. We never sell your personal information to third [...] http://digg.com/u1I6EM
Name
URL
Description
Name
URL
Description
innate immune responses
Innate Immune Database (IIDB)
http://ping.fm/9TJc4
Genes involved with immune responses
JenPep
http://ping.fm/Z3VVB
Protein-peptide interactions in the immune system
InnateImmunity-SystemsBiology.org
http://ping.fm/L2ma3
Innate immunity, inflammation, septic shock
Pathogen Interaction Gateway (PIG)
http://ping.fm/U2mqG
Host-pathogen, protein-protein interactions
VirusMINT
http://ping.fm/wLfFF
Human-viral protein interactions
NetPath
http://www.netpath.org/
Pathways in humans, including immune pathways
KEGG
http://ping.fm/ntBJc
Pathway maps, tables, catalogs
Reactome
www.reactome.org/
A pathway database
HPRD
http://www.hprd.org/
Pathways and interaction database
GenMapp
http://www.genmapp.org/
Pathway tools
BioCyc
http://www.biocyc.org/
Pathway databases
Pathguide
http://ping.fm/6JWFL
The pathway resource [...] http://digg.com/u1Ge7E
Name
URL
Content
Name
URL
Description
Name
URL
Description
(BLAST)
http://ping.fm/WhkZs
Sequence comparison
CLUSTAL W
http://ping.fm/3qI96
A tool for sequence alignment
Motif Scan
http://ping.fm/TIFwd
Finding sequence motifs/patterns
PredictProtein
http://ping.fm/hxnVK
Prediction of protein secondary structures
Protein Data Bank (PDB)
http://ping.fm/SdOk6
3D structure data
Molecular Modeling Database [...] http://digg.com/u1GdFc
URL
Description
Immune Epitope Database
and Analysis Resource (IEDB)
AntiJen Database
T, B cell epitopes, TAP
Epitome
CED
MIMOX
EpiJen
MHCPred
peptide-MHC binding
RankPep
EPIMHC
Herbs and Herbal Extracts
Ginseng and Salviae
Effects and Interactions
The herbs may have anti-influenza effects. Ginseng and Salviae may be used as potential mucosal adjuvants against influenza viruses. They may serve as immuno-modulators during influenza virus infection (Quan et al., 2007).
Mechanisms
Co-administration of influenza virus A (PR8) vaccine and ginseng or Salviae extract? may have
Enhanced [...]
Nutrients
Polyphenols
Herbs and Herbal Extracts
The aerial roots of Geranium sanguineum L. (PC)
Effects and Interactions
The herb may have anti-influenza effects. A polyphenol-rich extract from the aerial roots of Geranium sanguineum L. (PC) has been found to protect mice from mortality in the A/Aichi/2/68 (H3N2) influenza infection (Serkedjieva et al., 2008). At the dose of 5.4 [...] http://digg.com/u1G2aA
Nutrients
Flavonoids
Herbs and Herbal Extracts
Flavonoids from Elsholtzia rugulosa (Lamiaceae)
General Background
It is a Chinese herb generally used for healing cold and fever.
Effects and Interactions
Flavonoids extracted from the herb have anti-influenza activities. Specifically, the herbal extract can inhibit the neuraminidase (NA) segment of influenza (Liu et al., 2008).
Reference
Liu, A. L., [...]
Herbs and Herbal Extracts
Crude extraction from Cochinchina momordica seeds (ECMS) through ethanol extraction.
General Background
Cochinchina momordica is a traditional Chinese medicinal herb (called ?Mu Bie Zi? in Chinese).
Effects and Interactions
Crude extraction from Cochinchina momordica seeds (ECMS) has been found to be a potential adjuvant for the improvement of the immune responses [...]
ABCA1 Transporter: Disease Association:
Coronary Disease:
- The R219K polymorphism of ABCA1 is related with altered lipoprotein levels, and may affect the high-density lipoprotein-cholesterol (HDL-C) response to pravastatin in Chinese patients with coronary heart disease (CHD).
(Effect of R219K polymorphism of the ABCA1 gene on the lipid-lowering effect of pravastatin in Chinese patients with coronary heart disease. Li [...] http://digg.com/u1FoP5
Nutrients
Polyphenols
Herbal extracts
50% ethanol extract of the fruit of Chaenomeles sinensis (?Mu Gua? in Chinese)
General Background
It is a traditional Chinese medicine to treat throat diseases.
Effects and Interactions
The herbal extract may have antiviral effects. High molecular weight polyphenols in the fruit extract can inhibit influenza viruses. Treatment with the extract at concentrations higher than [...] http://digg.com/u1FmlV
ABCA1 Transporter: Tissue Distribution
Macrophages:
Tissue-specific roles of ABCA1 influence susceptibility to atherosclerosis. Brunham LR, Singaraja RR, Duong M, Timmins JM, Fievet C, Bissada N, Kang MH, Samra A, Fruchart JC, McManus B, Staels B, Parks JS, Hayden MR. Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):548-54. Epub 2009 Feb 5. PMID: 19201688
Alternate transcripts expressed in response to [...] http://digg.com/u1FjKD
Flavonoids
Nutrients
Flavonoids
General Background
Flavonoids are polyphenols and commonly found in herbs. Researchers studied the structure-activity relationship (SAR) of 25 flavonoids and their effects on the neuraminidase (NA) gene of influenza virus (Liu et al., 2008). They used three typical influenza virus strains A/PR/8/34 (H1N1), A/Jinan/15/90 (H3N2), and B/Jiangshu/10/2003.
Effects and [...]
ABCA1
Polymorphisms/Variants/SNPs/Pharmacogenomics
dbSNP
SNP VarView
GeneView in dbSNP
Prediction:
Accurate prediction of the functional significance of single nucleotide polymorphisms and mutations in the ABCA1 gene. Brunham LR, Singaraja RR, Pape TD, Kejariwal A, Thomas PD, Hayden MR. PLoS Genet. 2005 Dec;1(6):e83. Epub 2005 Dec 30. PMID: 16429166
Alzheimer?s Disease:
A novel intronic polymorphism of ABCA1 gene reveals risk for sporadic Alzheimer’s disease [...] http://digg.com/u1Ff4i
Full Name
ATP-binding cassette, sub-family A (ABC1), member 1 [Homo sapiens]
Symbol
ABCA1
Other Symbols
ABC-1, ABC1, CERP, FLJ14958, HDLDT1, MGC164864, MGC165011, TGD
Other Names
ATP binding cassette transporter 1; ATP-binding cassette 1; ATP-binding cassette transporter A1; ATP-binding cassette, sub-family A member 1; cholesterol efflux regulatory protein; membrane-bound
Chromosome Location
9q31.1
Map Viewer
Gene ID
19
OMIM ID
600046
OMIM
Family
ATP-binding cassette, sub-family A
Classification
3.A.1.211.1
Sequences
Nucleotide
Protein
Functions
A cholesteral efflux pump
Posts
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