Databases and Tools for Analysis of Genetic Variations of the Immune System

Name

URL

Description

IPD
http://ping.fm/gAzEx
Immuno-polymorphism database


dbMHC
http://ping.fm/flWaj
MHC DNA and clinical


dbLRC
http://ping.fm/lpd4Z
Database of human Leukocyte Receptor Complex (LRC)


MHC Haplotype Project
http://ping.fm/60gXp
Association studies of MHC-related diseases


SNEP
http://ping.fm/p6ddS
Prediction of SNP-derived epitopes


SiPep (SNPBinder)
http://www.sipep.org/
Prediction of minor histocompatibility antigens


International HapMap Project
http://snp.cshl.org/
Databases of sequence variations


dbSNP
http://ping.fm/5lvdb
NCBI’s database of SNPs


Allele Frequencies Database
http://ping.fm/kjBKO
On alleles in human populations



http://digg.com/u1Gddm

Databases and Tools for Structure-Function Analysis of the Immune System

Name

URL

Description

IMGT®, the international ImMunoGeneTics information system®
http://imgt.cines.fr/
Database of the IG, TR, MHC, IgSF, MhcSF and RPI


ABG
http://ping.fm/sdC2M
Antibody 3D structures


Immunome
http://ping.fm/fNLG9
Immunity related proteins, structures, ontology terms


Basic Local Alignment Search Tool

(BLAST)
http://ping.fm/WhkZs
Sequence comparison


CLUSTAL W
http://ping.fm/3qI96
A tool for sequence alignment


Motif Scan
http://ping.fm/TIFwd
Finding sequence motifs/patterns


PredictProtein
http://ping.fm/hxnVK
Prediction of protein secondary structures


Protein Data Bank (PDB)
http://ping.fm/SdOk6
3D structure data


Molecular Modeling Database [...] http://digg.com/u1GdFc

Immunoinformatics Databases and Tools for T Cells, B Cells, and Epitope Analyses

Name

URL

Description

Immune Epitope Database

and Analysis Resource (IEDB)

http://ping.fm/Acr5a
Database of antibody, T cell epitopes

AntiJen Database

http://ping.fm/l4zT7
Database of peptide-MHC binding,

T, B cell epitopes, TAP

Epitome

http://ping.fm/1B3Nh
Database of antigenic epitopes

CED

http://ping.fm/rsKlj
Conformational Epitope Database

MIMOX

http://ping.fm/EDr2N
Phage display based epitope mapping

EpiJen

http://ping.fm/Qc46z
Prediction of T cell epitopes

MHCPred

http://ping.fm/ExBVs
Quantitative prediction of

peptide-MHC binding

RankPep

http://ping.fm/C7n1Q
Prediction of peptide-MHC binding

EPIMHC

http://ping.fm/kSiew
Database of [...] http://digg.com/u1GdFa

Anti-Influenza Herbs: Ginseng and Salviae

Herbs and Herbal Extracts

Ginseng and Salviae

Effects and Interactions

The herbs may have anti-influenza effects. Ginseng and Salviae may be used as potential mucosal adjuvants against influenza viruses. They may serve as immuno-modulators during influenza virus infection (Quan et al., 2007).

Mechanisms

Co-administration of influenza virus A (PR8) vaccine and ginseng or Salviae extract? may have

Enhanced [...]

http://digg.com/u1G75V

Anti-Influenza Herb: Geranium sanguineum L. (PC)

Nutrients

Polyphenols

Herbs and Herbal Extracts

The aerial roots of Geranium sanguineum L. (PC)

Effects and Interactions

The herb may have anti-influenza effects. A polyphenol-rich extract from the aerial roots of Geranium sanguineum L. (PC) has been found to protect mice from mortality in the A/Aichi/2/68 (H3N2) influenza infection (Serkedjieva et al., 2008). At the dose of 5.4 [...] http://digg.com/u1G2aA

Anti-Influenza Herb: Elsholtzia rugulosa (Lamiaceae)

Nutrients

Flavonoids

Herbs and Herbal Extracts

Flavonoids from Elsholtzia rugulosa (Lamiaceae)

General Background

It is a Chinese herb generally used for healing cold and fever.

Effects and Interactions

Flavonoids extracted from the herb have anti-influenza activities. Specifically, the herbal extract can inhibit the neuraminidase (NA) segment of influenza (Liu et al., 2008).

Reference

Liu, A. L., [...]

http://digg.com/u1FyWe

Anti-Influenza Herb: Cochinchina Momordica As A Potential Adjuvant for Influenza Vaccines

Herbs and Herbal Extracts

Crude extraction from Cochinchina momordica seeds (ECMS) through ethanol extraction.

General Background

Cochinchina momordica is a traditional Chinese medicinal herb (called ?Mu Bie Zi? in Chinese).

Effects and Interactions

Crude extraction from Cochinchina momordica seeds (ECMS) has been found to be a potential adjuvant for the improvement of the immune responses [...]

http://digg.com/u1FrRn